2024-03-29T13:08:07Zhttp://oai.recercat.cat/request
oai:recercat.cat:2072/2476762015-03-12T23:17:50Zhdl_2072_179329
RECERCAT (Diposit de la Recerca de Catalunya)
Universitat de Barcelona
authorvon Reth, Marcel
authorAlcázar Hernández, Rubén
2014
http://hdl.handle.net/2445/63971
A long-standing question in evolutionary biology is what defines a species. The biological species concept considers a species as a population of individuals that interbreeds freely and produces viable offspring. Therefore, reproductive isolation is the essence of species. Hybrid necrosis is one form of post-zygotic reproductive isolation. In this chapter, we summarize what is known to date about this phenomenon and highlight progress made in the understanding of these immune-triggered hybrid incompatibilities through our research in the plant model Arabidopsis thaliana.
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/63704
18 p.
application/pdf
eng
Research Signpost
Reproducció del capítol del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=234
Recent Advances in Pharmaceutical Sciences IV, 2014, Research Signpost : Editors: Diego Muñoz Torrero, Manuel Vázquez-Carrera & Joan Estelrich i Latràs. ISBN: 978-81-308-0554-2. Chapter 3, p. 37-54.
http://hdl.handle.net/2445/63704
(c) Research Signpost, 2014
info:eu-repo/semantics/openAccess
Arabidopsis thaliana
Biologia molecular vegetal
Fisiologia vegetal
Plant molecular biology
Plant physiology
The evolution of post-zygotic isolation barriers by immune-triggered hybrid incompatibilities in Arabidopsis thaliana
info:eu-repo/semantics/bookPart
oai:recercat.cat:2072/2479182015-03-19T23:13:07Zhdl_2072_179329
RECERCAT (Diposit de la Recerca de Catalunya)
Universitat de Barcelona
authorTres Oliver, Alba
authorCodony Salcedo, Rafael
authorGuardiola Ibarz, Francesc
2014
http://hdl.handle.net/2445/64324
Organic food products are highly susceptible to fraud. Currently, administrative controls are conducted to detect fraud, but having an analytical tool able to verify the organic identity of food would be very supportive. The state-of-the-art in food authentication relies on fingerprinting approaches that find characteristic analytical patterns to unequivocally identify authentic products. While wide research on authentication has been conducted for other commodities, the authentication of organic chicken products is still in its infancy. Challenges include finding fingerprints to discriminate organic from conventional products, and recruiting sample sets that cover natural variability. Future research might be oriented towards developing new authentication models for organic feed, eggs and chicken meat, keeping models updated and implementing them into regulations. Meanwhile, these models might be very supportive to the administrative controls directing inspections towards suspicious fraudulent samples.
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/63704
19 p.
application/pdf
eng
Research Signpost
Reproducció del capítol del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=234
Recent Advances in Pharmaceutical Sciences IV, 2014, Research Signpost : Editors: Diego Muñoz Torrero, Manuel Vázquez-Carrera & Joan Estelrich i Latràs. ISBN: 978-81-308-0554-2. Chapter 7, p. 99-117.
http://hdl.handle.net/2445/63704
(c) Research Signpost, 2014
info:eu-repo/semantics/openAccess
Aliments naturals
Pollastre
Inspecció dels aliments
Natural foods
Chicken
Food inspection
Organic chicken product authentication: state-of-the-art and future perspectives
info:eu-repo/semantics/bookPart
oai:recercat.cat:2072/2480012015-03-20T23:12:09Zhdl_2072_179329
RECERCAT (Diposit de la Recerca de Catalunya)
Universitat de Barcelona
authorModamio Charles, Pilar
authorRuiz Loscertales, Héctor
authorBraza Reyes, Antonio J.
authorTobaruela Martínez, Gonzalo
authorFernández Lastra, Cecilia
authorMariño Hernández, Eduardo L.
2014
http://hdl.handle.net/2445/64366
A multicompartment compliance aid (MCA) is a blister-type repackaging system that aims to facilitate drug administration and thereby increase patient adherence. One of the characteristics of the MCA that should be taken into account is the moisture permeability, since this atmospheric condition is one of the most important factors that can modify the stability of medicines. In the current paper we report the moisture permeability tests performed on a MCA according to the US Pharmacopeia. This information on the suitability of the device will help pharmacists implement a high-quality professional service.
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/63704
10 p.
application/pdf
eng
Research Signpost
Reproducció del capítol del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=234
Recent Advances in Pharmaceutical Sciences IV, 2014, Research Signpost : Editors: Diego Muñoz Torrero, Manuel Vázquez-Carrera & Joan Estelrich i Latràs. ISBN: 978-81-308-0554-2. Chapter 9, p. 133-142.
http://hdl.handle.net/2445/63704
(c) Research Signpost, 2014
info:eu-repo/semantics/openAccess
Envasament dels medicaments
Administració de medicaments
Estabilitat dels medicaments
Serveis farmacèutics
Drugs packaging
Administration of drugs
Drug stability
Pharmaceutical services
Degree of hermeticity of a multicompartment compliance aid: Implications for the quality of professional pharmaceutical services
info:eu-repo/semantics/bookPart
oai:recercat.cat:2072/2480032015-03-20T23:12:12Zhdl_2072_179329
RECERCAT (Diposit de la Recerca de Catalunya)
Universitat de Barcelona
authorGiménez Claudio, Rosa
authorAguilera Gil, Maria Laura
authorFerreira, Elaine
authorAguilar Piera, Juan
authorBaldomà Llavinés, Laura
authorBadía Palacín, Josefa
2014
http://hdl.handle.net/2445/64368
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is considered a housekeeping protein that is present in virtually all organisms, where it performs metabolic functions essential for survival. GAPDH plays an essential role in the process of energy production, and is also involved in numerous biological processes. GAPDH belongs to a subset of proteins called moonlighting proteins, in which different functions are associated with a single polypeptide chain. The multifunctionality of GAPDH has been described in pathogenic and probiotic microorganisms, in mammals and in plants. In this review, we summarize the moonlighting role of GAPDH in bacteria.
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/63704
16 p.
application/pdf
eng
Research Signpost
Reproducció del capítol del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=234
Recent Advances in Pharmaceutical Sciences IV, 2014, Research Signpost : Editors: Diego Muñoz Torrero, Manuel Vázquez-Carrera & Joan Estelrich i Latràs. ISBN: 978-81-308-0554-2. Chapter 11, p. 165-180.
http://hdl.handle.net/2445/63704
(c) Research Signpost, 2014
info:eu-repo/semantics/openAccess
Oxidoreductases
Bacteris
Bioquímica
Oxidoreductases
Bacteria
Biochemistry
Glyceraldehyde-3-phosphate dehydrogenase as a moonlighting protein in bacteria
info:eu-repo/semantics/bookPart
oai:recercat.cat:2072/2552712015-10-29T23:26:58Zhdl_2072_179329
RECERCAT (Diposit de la Recerca de Catalunya)
Universitat de Barcelona
authorBaratier, Célia
authorCortés Lucas, Amparo
2015
http://hdl.handle.net/2445/67541
Human health risk assessment is the basis for groundwatercontamination and remediation goals definitions. Chlorinated solventshave a high toxicity for humans, even at low concentrations, and areimportant soil and groundwater pollutants. The main objective of thiswork is to assess the human health risk derived of exposition to acontaminated groundwater using a commercial Risk Analysis model(RBCA) and taking into consideration different exposure factors. Acase study was used. Some risk differences were observed usingspecific exposure factors in different countries, which were explainedby differences in life style.
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/67430
19 p.
application/pdf
eng
Research Signpost
Reproducció del capítol del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=249
Recent Advances in Pharmaceutical Sciences V, 2015, Research Signpost. Editors: Diego Muñoz Torrero, M. Pilar Vinardell & Javier Palazón. ISBN: 978-81-308-0561-0. Chapter 2, p. 13-31.
http://hdl.handle.net/2445/67430
(c) Research Signpost, 2015
info:eu-repo/semantics/openAccess
Compostos organoclorats
Contaminació de l'aigua
Avaluació del risc per la salut
Higiène ambiental
Organochlorine compounds
Water pollution
Health risk assessment
Environmental health
Detailed human risk assessment arising from groundwater contaminated by chlorinated hydrocarbons (DNAPLs)
info:eu-repo/semantics/bookPart
oai:recercat.cat:2072/2552722015-10-29T23:27:00Zhdl_2072_179329
RECERCAT (Diposit de la Recerca de Catalunya)
Universitat de Barcelona
authorBonfill Baldrich, Ma. Mercedes
authorCusidó Vidal, Rosa M.
authorLalaleo, Liliana
authorPalazón Barandela, Javier
2015
http://hdl.handle.net/2445/67542
Plant cell and organ cultures constitute a promisingplatform for the production of numerous valuable secondarycompounds. Currently, in vitro culture techniques involve bothempirical and rational approaches as suitable strategies to conditionhigh metabolite production and establish competitive plant cell-basedbioprocesses. In this context, we have developed hairy root cultures ofPanax ginseng, and engineered hairy root cultures of Duboisia,Datura metel and Hyoscyamus spp and plant cell cultures of Centellaasiatica and Taxus spp. This chapter describes our work on thedevelopment of two different biotechnological systems to improvetaxol production in cell suspension cultures of Taxus spp andginsenoside production in hairy root cultures of Panax ginseng.
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/67430
17 p.
application/pdf
eng
Research Signpost
Reproducció del capítol del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=249
Recent Advances in Pharmaceutical Sciences V, 2015, Research Signpost. Editors: Diego Muñoz Torrero, M. Pilar Vinardell & Javier Palazón. ISBN: 978-81-308-0561-0. Chapter 3, p. 33-49.
http://hdl.handle.net/2445/67430
(c) Research Signpost, 2015
info:eu-repo/semantics/openAccess
Cultiu de cèl·lules i teixits vegetals
Fitoquímica
Fisiologia vegetal
Plant cell and tissue culture
Botanical chemistry
Plant physiology
Plant cell and organ cultures as a source of phytochemicals
info:eu-repo/semantics/bookPart
oai:recercat.cat:2072/2552732015-10-29T23:27:00Zhdl_2072_179329
RECERCAT (Diposit de la Recerca de Catalunya)
Universitat de Barcelona
authorIzquierdo Pulido, María Luz
authorRíos Hernández, Alejandra
authorFarran, Andreu
authorAlda, José Ángel
2015
http://hdl.handle.net/2445/67543
ADHD (Attention Deficit and Hyperactive Disorder) is the most common neurobehavioral disorder of childhood, presenting with pervasive and impairing symptoms of inattention, hyperactivity, impulsivity, or a combination. There is scientific evidence that some dietary and physical activity strategies may be useful to improve the symptoms of ADHD and benefit the social, cognitive and academic performance of children and adolescents with ADHD. The purpose of our study was to review the scientific literature on the role of diet and physical activity in ADHD symptomatology up to date.
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/67430
14 p.
application/pdf
eng
Research Signpost
Reproducció del capítol del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=249
Recent Advances in Pharmaceutical Sciences V, 2015, Research Signpost. Editors: Diego Muñoz Torrero, M. Pilar Vinardell & Javier Palazón. ISBN: 978-81-308-0561-0. Chapter 4, p. 51-64.
http://hdl.handle.net/2445/67430
(c) Research Signpost, 2015
info:eu-repo/semantics/openAccess
Trastorns per dèficit d'atenció amb hiperactivitat en els infants
Dietoteràpia
Exercici
Nutrició
Attention deficit disorder with hyperactivity in children
Diet therapy
Exercise
Nutrition
The role of diet and physical activity in children and adolescents with ADHD
info:eu-repo/semantics/bookPart
oai:recercat.cat:2072/2552872015-10-30T23:21:53Zhdl_2072_179329
RECERCAT (Diposit de la Recerca de Catalunya)
Universitat de Barcelona
authorVitales Serrano, Daniel
authorPellicer Moscardó, Jaume
authorVallès Xirau, Joan, 1959-
authorGarnatje i Roca, Teresa
2015
http://hdl.handle.net/2445/67557
The diversification of Cheirolophus in Macaronesian archipelagos constitutes a paradigmatic example of radiation on oceanic islands. Phylogenetic and molecular dating analyses indicate an extraordinarily fast process, showing one of the highest speciation rates ever found on plants from oceanic islands. Such radiation has been recently studied employing phylogeographic, population genetic and molecular cytogenetic approaches. Here, the main potential patterns and processes involved in the diversification of the genus in the Canary Islands and Madeira are reviewed and discussed as a whole.
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/67430
16 p.
application/pdf
eng
Research Signpost
Reproducció del capítol del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=249
Recent Advances in Pharmaceutical Sciences V, 2015, Research Signpost. Editors: Diego Muñoz Torrero, M. Pilar Vinardell & Javier Palazón. ISBN: 978-81-308-0561-0. Chapter 6, p. 85-100.
http://hdl.handle.net/2445/67430
(c) Research Signpost, 2015
info:eu-repo/semantics/openAccess
Compostes
Macaronèsia
Filogènia (Botànica)
Filogeografia
Citogenètica
Botànica
Compositae
Macaronesia
Phylogeny (Botany)
Phylogeography
Cytogenetics
Botany
Molecular insights into the diversification of Cheirolophus (Asteraceae) in Macaronesia
info:eu-repo/semantics/bookPart
oai:recercat.cat:2072/2552882015-10-30T23:21:56Zhdl_2072_179329
RECERCAT (Diposit de la Recerca de Catalunya)
Universitat de Barcelona
authorMiquel Colomé, Jordi
authorTorres Martínez, Jordi
authorFeliu José, Carlos
2015
http://hdl.handle.net/2445/67558
The usefulness of the ultrastructural characters of spermiogenesis and of the spermatozoon in the interpretation of relationships in the Platyhelminthes has been widely demonstrated. The present paper provides a review and an update on the ultrastructural knowledge on spermiogenesis and on the spermatozoon in cyclophyllidean cestodes. For each family of cyclophyllideans the pattern of spermiogenesis and the type of sperm cell is provided. Moreover, the most interesting characteristics of both spermiogenesis and the spermatozoon are compiled and illustrated for each family. Finally, new spermatological data on some species of the Anoplocephalidae and the Taeniidae are provided.
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/67430
15 p.
application/pdf
eng
Research Signpost
Reproducció del capítol del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=249
Recent Advances in Pharmaceutical Sciences V, 2015, Research Signpost. Editors: Diego Muñoz Torrero, M. Pilar Vinardell & Javier Palazón. ISBN: 978-81-308-0561-0. Chapter 7, p. 101-115.
http://hdl.handle.net/2445/67430
(c) Research Signpost, 2015
info:eu-repo/semantics/openAccess
Espermatogènesi
Espermatozoides
Cestodes
Ultraestructura (Biologia)
Parasitologia
Spermatogenesis
Spermatozoa
Tapeworms
Ultrastructure (Biology)
Parasitology
Ultrastructure of spermiogenesis and the spermatozoon in cyclophyllidean cestodes
info:eu-repo/semantics/bookPart
oai:recercat.cat:2072/2552912015-10-30T23:22:00Zhdl_2072_179329
RECERCAT (Diposit de la Recerca de Catalunya)
Universitat de Barcelona
authorMartín Arjol, Ignacio
authorBusquets Abió, Montserrat
authorManresa Presas, Ma. Ángeles (María Ángeles)
2015
http://hdl.handle.net/2445/67563
Oxylipins are a family of natural compounds that are reported to perform a variety of biological functions. Besides the biological properties of such compounds, interest in hydroxy fatty acids is increasing, due to the industrial applications of these renewable compounds as a starting material for resins, emulsifiers, plastics or polyesters. Hydroxy fatty acids are used as thickeners in a new generation of emulsifiers and lubricants, to reach new levels of performance. When grown in submerged culture with oleic or linoleic acid, Pseudomonas aeruginosa 42A2 produced several oxylipins. In this study, oxylipin production and its applications are examined.
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/67430
17 p.
application/pdf
eng
Research Signpost
Reproducció del capítol del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=249
Recent Advances in Pharmaceutical Sciences V, 2015, Research Signpost. Editors: Diego Muñoz Torrero, M. Pilar Vinardell & Javier Palazón. ISBN: 978-81-308-0561-0. Chapter 10, p. 149-165.
http://hdl.handle.net/2445/67430
(c) Research Signpost, 2015
info:eu-repo/semantics/openAccess
Productes naturals
Pseudomonas
Microbiologia
Natural products
Pseudomonas
Microbiology
Production of bacterial oxylipins by Pseudomonas aeruginosa 42A2
info:eu-repo/semantics/bookPart
oai:recercat.cat:2072/2551642015-11-02T23:14:08Zhdl_2072_179329
RECERCAT (Diposit de la Recerca de Catalunya)
Universitat de Barcelona
authorDelgado Cirilo, Antonio
authorCasas Brugulat, Josefina
authorAbad Saiz, José Luis
authorFabriàs Domingo, Gemma
2015
http://hdl.handle.net/2445/67431
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/67430
12 p.
application/pdf
eng
Research Signpost
Reproducció del capítol del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=249
Recent Advances in Pharmaceutical Sciences V, 2015, Research Signpost. Editors: Diego Muñoz Torrero, M. Pilar Vinardell & Javier Palazón. ISBN: 978-81-308-0561-0. Chapter 1, p. 1-12.
http://hdl.handle.net/2445/67430
(c) Research Signpost, 2015
info:eu-repo/semantics/openAccess
Esfingolípids
Química orgànica
Sphingolipids
Organic chemistry
Chemical approaches to sphingolipid research
info:eu-repo/semantics/bookPart
oai:recercat.cat:2072/2552922015-11-02T23:14:10Zhdl_2072_179329
RECERCAT (Diposit de la Recerca de Catalunya)
Universitat de Barcelona
authorPalomer Tarridas, Francesc Xavier
authorBarroso Fernández, Emma
authorVázquez Carrera, Manuel
2015
http://hdl.handle.net/2445/67564
Diabetic cardiomyopathy is characterized by structural and functional alterations in the heart muscle of people with diabetes that finally lead to heart failure. Metabolic disturbances characterized by increased lipid oxidation, intramyocardial triglyceride accumulation and reduced glucose utilization have all been involved in the pathogenesis of diabetic cardiomyopathy. On the other hand, evidences arisen in the recent years point to a potential link between chronic low-grade inflammation in the heart and metabolic dysregulation. Interestingly, the progression of heart failure and cardiac hypertrophy usually entails the activation of pro-inflammatory pathways. Therefore, in this chapter we summarize novel insights into the crosstalk between inflammatory processes and metabolic dysregulation in the failing heart during diabetes.
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/67430
20 p.
application/pdf
eng
Research Signpost
Reproducció del capítol del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=249
Recent Advances in Pharmaceutical Sciences V, 2015, Research Signpost. Editors: Diego Muñoz Torrero, M. Pilar Vinardell & Javier Palazón. ISBN: 978-81-308-0561-0. Chapter 11, p. 167-186.
http://hdl.handle.net/2445/67430
(c) Research Signpost, 2015
info:eu-repo/semantics/openAccess
Complicacions de la diabetis
Miocardiopaties
Farmacologia
Diabetes complications
Myocardiopathies
Pharmacology
Inflammation and metabolic dysregulation in diabetic cardiomyopathy
info:eu-repo/semantics/bookPart
oai:recercat.cat:2072/2021632016-03-04T08:28:37Zhdl_2072_179329
RECERCAT (Diposit de la Recerca de Catalunya)
Universitat de Barcelona
authorArróniz, Carlos
authorEscolano Mirón, Carmen
2012-10-04T12:30:05Z
2012-10-04T12:30:05Z
2012
http://hdl.handle.net/2445/32194
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/32393
The preparation of enantiomerically pure compounds (EPC) is a continuous social demand due to the clinical advantages that enantiopure drugs offer over the racemic forms. Here, the best
well-established synthetic strategies to access to single-enantiomer compounds are briefly described and compared. In particular, the enantioselective catalysis is introduced paying special attention to the organocatalysis, an emerging and fruitful area in the EPCsynthesis.
Of particular interest is the use of small organic molecules as catalysts in cascade reactions. Organocascade reactions involve the formation of several chemical bonds and
often generate stereogenic centers with excellent stereoselectivity. Such one-pot reactions avoid time-consuming and costly step-bystep
processes and are environmentally friendly as they occur in the absence of metals. Additionally, the chemical waste of the
organocatytic cascade reactions is drastically reduced since the intermediates are not isolated and purified.
20 p.
application/pdf
eng
Transworld Research Network
Reproducció del capítol 7 del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=131
Recent Advances in Pharmaceutical Sciences II, 2012, Editor: Diego Muñoz-Torrero, Diego Haro and Joan Vallès, Chapter 7, p. 115-134.
(c) Transworld Research Network , 2012
info:eu-repo/semantics/openAccess
Farmacologia
Enantiòmers
Medicaments
Pharmacology
Enantiomers
Drugs
Strategies for the synthesis of enantiopure compounds focused on organocatalysis
info:eu-repo/semantics/bookPart
oai:recercat.cat:2072/1795322016-03-15T23:50:26Zhdl_2072_179329
RECERCAT (Diposit de la Recerca de Catalunya)
Universitat de Barcelona
authorEscubedo Rafa, Elena
authorGarcia Ratés, Sara
authorCamarasa García, Jordi
authorPubill Sánchez, David
2012-01-09T11:07:41Z
2012-01-09T11:07:41Z
2011
2011-12-27T14:25:59Z
258429
http://hdl.handle.net/2445/21373
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/32392
During the last years, our emphasis has focused in the study of the neurotoxic effects of 3,4-methylenedioxymethamphetamine (MDMA) and methamphetamine (METH) on central nervous system and their pharmacological prevention. In the process of this research, we have used a semipurified synaptosomal preparation from striatum of mice or rats as a reliable in vitro model to study reactive oxygen species (ROS) production by these amphetamine derivatives, which is well correlated with their dopaminergic injury in in vivo models. Using this preparation we have demonstrated that blockade of alpha7 nicotinic receptors with methyllycaconitine (MLA) and memantine (MEM) prevents ROS production induced by MDMA and METH. Studies at molecular level showed that both, MDMA and METH, displaced competitively the binding of radioligands for homomeric alpha7 and heteromeric nAChRs, indicating that they can directly interact with them. In all the cases MDMA displayed higher affinity than METH and it was higher for heteromeric than for alpha7 subtype. Preincubation of differentiated PC12 cells with MDMA or METH induces nicotinic acetylcholine receptors (nAChR) up-regulation in a concentration- and time-dependent manner, as many nicotinic ligands do, supporting their functional interaction with nAChRs. Such interaction expands the pharmacological profile of amphetamines and can account for some of their effects.
20 p.
application/pdf
eng
Transworld Research Network
Reproducció del capítol 7 del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=149
Recent Advances in Pharmaceutical Sciences, 2011, Chapter 7, p. 155-174, Editor: Diego Muñoz-Torrero
http://hdl.handle.net/2445/32392
(c) Transworld Research Network, 2011
info:eu-repo/semantics/openAccess
Receptors nicotínics
Amfetamines
Nicotinic receptors
Amphetamines
Involvement of nicotinic receptors in methamphetamine and MDMA induced neurotoxicity: Pharmacological studies
info:eu-repo/semantics/bookPart
oai:recercat.cat:2072/2476542016-04-28T22:52:39Zhdl_2072_179329
RECERCAT (Diposit de la Recerca de Catalunya)
Universitat de Barcelona
authorBaena Muñoz, Miguel
authorSangüesa Puigventós, Gemma
authorHutter, Natalia
authorSánchez Peñarroya, Rosa M.
authorLaguna Egea, Juan Carlos
authorAlegret i Jordà, Marta
authorRoglans i Ribas, Núria
2015-03-11T13:20:09Z
2015-03-11T13:20:09Z
2014
http://hdl.handle.net/2445/63891
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/63704
Global changes in dietary habits in the last decades caused an increase of added sugar consumption all over the world, which has been linked to the increasing prevalence of obesity, dyslipidemia, insulin resistance and cardiovascular disease. Fructose is widely used as a sweetener in the food and beverage industry, either as an integrant of the sucrose molecule or as a component of high fructose corn syrups. The consumption of fructose in beverages is especially dangerous, as the process of energy compensation by reduction in the ingestion of other foods does not work equally well with liquid than solid foods. Besides, fructose is the carbohydrate with the highest ability to induce hypertriglyceridemia, due to a marked increase in lipogenesis compared with glucose. In this review we will discuss some of the most recent studies performed in animal models and in humans to investigate the effects of excessive fructose consumption.
19 p.
application/pdf
eng
Research Signpost
Reproducció del capítol del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=234
Recent Advances in Pharmaceutical Sciences IV, 2014, Research Signpost: Editors: Diego Muñoz Torrero, Manuel Vázquez-Carrera & Joan Estelrich i Latràs. ISBN: 978-81-308-0554-2. Chapter 1, p. 1-19.
http://hdl.handle.net/2445/63704
(c) Research Signpost, 2014
info:eu-repo/semantics/openAccess
Fructosa
Trastorns del metabolisme
Models animals en la investigació
Fructose
Disorders of metabolism
Animal models in research
Fructose effects on human health: Molecular insights from experimental models
info:eu-repo/semantics/bookPart
oai:recercat.cat:2072/2678272016-11-08T23:33:21Zhdl_2072_179329
RECERCAT (Diposit de la Recerca de Catalunya)
Universitat de Barcelona
authorTresserra Rimbau, Anna
authorLamuela Raventós, Rosa Ma.
2016-11-08T15:21:00Z
2016-11-08T15:21:00Z
2016
http://hdl.handle.net/2445/103448
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/103042
Polyphenols are a large and heterogeneous group of compounds widely distributed in fruits, vegetables, cereals and their products such as coffee or wine. These bioactive compounds can ameliorate our health by improving certain risk factors, especially the cardiovascular ones. Thus, many investigations have focused on the effects of some polyphenols and polyphenol-rich foods on cardiovascular and other chronic diseases.
20 p.
application/pdf
eng
Research Signpost
Reproducció del capítol del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=267
Recent Advances in Pharmaceutical Sciences VI, 2016, Research Signpost. Editors: Diego Muñoz Torrero, Àngela Domínguez García & Ma. Ángeles Manresa Presas. ISBN: 978-81-308-0566-5. Chapter 2, p. 17-36.
http://hdl.handle.net/2445/103042
(c) Research Signpost, 2016
info:eu-repo/semantics/openAccess
Polifenols
Malalties cardiovasculars
Polyphenols
Cardiovascular diseases
Benefits of polyphenol intake on the cardiovascular risk parameter
info:eu-repo/semantics/bookPart
oai:recercat.cat:2072/2680482016-11-25T23:50:08Zhdl_2072_179329
RECERCAT (Diposit de la Recerca de Catalunya)
Universitat de Barcelona
authorCoronel León, Jonathan
authorManresa Presas, Ma. Ángeles (María Ángeles)
authorMarqués Villavecchia, Ana M.
2016-11-25T14:52:10Z
2016-11-25T14:52:10Z
2016
http://hdl.handle.net/2445/104173
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/103042
Lipopeptides such as lichenysin are biosurfactants of great interest, due to the demand for natural surface-active agents with low toxicity. Bacillus licheniformis AL 1.1 produces a lipopeptide characterized as lichenysin (LchAL1.1), which acts as a powerful surfactant, able to reduce surface tension to 28.5 mN m-1 and with a critical micelle concentration of 15 mg L-1. LchAL1.1 is particularly effective in preventing biofilm formation by pathogenic strains, has an emulsifying capacity and permeabilizes membranes by a colloid-osmotic process. The production of lipopeptides from agro-industrial residues, particularly molasses, is a sustainable process of great potential for the development of economic bioprocesses.
17 p.
application/pdf
eng
Research Signpost
Reproducció del capítol del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=267
Recent Advances in Pharmaceutical Sciences VI, 2016, Research Signpost. Editors: Diego Muñoz Torrero, Àngela Domínguez García & Ma. Ángeles Manresa Presas. ISBN: 978-81-308-0566-5. Chapter 9, p. 147-163.
http://hdl.handle.net/2445/103042
(c) Research Signpost, 2016
info:eu-repo/semantics/openAccess
Agents tensioactius
Surface active agents
Lichenysin production and application in the pharmaceutical field
info:eu-repo/semantics/bookPart
oai:recercat.cat:2072/2680492016-11-25T23:50:10Zhdl_2072_179329
RECERCAT (Diposit de la Recerca de Catalunya)
Universitat de Barcelona
authorPiqué i Clusella, Núria
authorPalau, Montserrat
authorBerlanga Herranz, Mercedes
authorMiñana i Galbis, David
2016-11-25T15:17:40Z
2016-11-25T15:17:40Z
2016
http://hdl.handle.net/2445/104174
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/103042
Helicobacter pylori is one of the human pathogens with highest prevalence around the world. Colonizing the human stomach, H. pylori could lead to peptic ulceration, gastric adenocarcinoma and gastric lymphoma. H. pylori is a genetically diverse bacterial species, and variability in virulence factors has a role in bacterial pathogenesis and progression to gastric cancer, although bacterium and host factors of progression are not completely understood. In a recent study, we have demonstrated that six housekeeping genes related to H. pylori pathogenesis were specifically amplified for H. pylori in a total of 52 H. pylori clones isolated from 11 patients. Although most clones isolated from the same patient showed identical gene sequences, events of multiple infection and microevolution were detected. We consider that housekeeping genes could be useful for H. pylori detection and to elucidate the mode of transmission and the relevance of the multiple infection. Further genetic studies are required to provide powerful tools to face all current unmet challenges of H. pylori infection, such as the elucidation of mode of transmission, the development of new sensitive and specific PCR methods for H. pylori detection, and implication of H. pylori in other diseases.
24 p.
application/pdf
eng
Research Signpost
Reproducció del capítol del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=267
Recent Advances in Pharmaceutical Sciences VI, 2016, Research Signpost. Editors: Diego Muñoz Torrero, Àngela Domínguez García & Ma. Ángeles Manresa Presas. ISBN: 978-81-308-0566-5. Chapter 10, p. 165-188.
http://hdl.handle.net/2445/103042
(c) Research Signpost, 2016
info:eu-repo/semantics/openAccess
Helicobacteri pilòric
Genètica bacteriana
Càncer
Aparell digestiu
Helicobacter pylori
Bacterial genetics
Cancer
Digestive organs
Advances in the research of new genetic markers for the detection of Helicobacter pylori infection
info:eu-repo/semantics/bookPart
oai:recercat.cat:2072/2680502016-12-01T01:26:40Zhdl_2072_179329
RECERCAT (Diposit de la Recerca de Catalunya)
Universitat de Barcelona
authorAlcover Amengual, Maria Magdalena
authorBallart Ferrer, J. Cristina
authorSerra, Teresa
authorPortús Vinyeta, Montserrat
authorGállego Culleré, M. (Montserrat)
2016-11-25T15:59:53Z
2016-11-25T15:59:53Z
2016
http://hdl.handle.net/2445/104176
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/103042
Data on leishmaniosis and its vectors (sand flies) in the Balearic Islands are scarce and restricted mainly to Majorca. According to the official data, the overall rate of human leishmaniosis (HL) is 0.7-3.5 cases per year/100,000 inhabitants (for the period 2001-2015), and the reported prevalence of canine leishmaniosis (CanL) varies between 0 and 45%, depending on the island and the dog population tested. In the present study, we investigated the sand fly fauna and current status of CanL in the Balearic Islands. Four sand fly species were captured: Phlebotomus perniciosus, a known vector in the Mediterranean area, P. sergenti, P. papatasi and Sergentomyia minuta. P. perniciosus was found throughout the island of Majorca, from sea level to the mountains, being detected in 70% of the capture sites and with a density of 6.7 specimens/m2. The global density of P. perniciosus in Minorca was of 3.4 specimens/m2, which constitutes a significant decrease compared to the results of a previous study performed 20 years ago. The influence of environmental factors on the presence or density of P. perniciosus differed according to the physiography of the area studied. A standard questionnaire sent to the local veterinarians in the Balearic Islands revealed that 73.8% of veterinarians had confirmed CanL cases in the previous 12 months and thought the disease was increasing in Minorca. The global seroprevalence of CanL in Minorca was 24%, being 31% among animals who had never left the island, which shows the existence of an autochthonous focus of CanL unrelated with an increasing vector density.
23 p.
application/pdf
eng
Research Signpost
Reproducció del capítol del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=267
Recent Advances in Pharmaceutical Sciences VI, 2016, Research Signpost. Editors: Diego Muñoz Torrero, Àngela Domínguez García & Ma. Ángeles Manresa Presas. ISBN: 978-81-308-0566-5. Chapter 11, p. 189-211.
http://hdl.handle.net/2445/103042
(c) Research Signpost, 2016
info:eu-repo/semantics/openAccess
Leishmaniosi
Illes Balears
Leishmaniasis
Balearic Islands
Current status of Leishmaniosis in the Balearic Islands
info:eu-repo/semantics/bookPart
oai:recercat.cat:2072/2552742017-10-12T05:34:42Zhdl_2072_179329
RECERCAT (Diposit de la Recerca de Catalunya)
Universitat de Barcelona
authorTeixidó Condomines, Elisabet
authorPiqué Benages, Maria Esther
authorBoix Sabrià, Núria
authorLlobet Mallafré, Joan M. (Joan Maria)
authorGómez Catalán, Jesús
2015-10-29T18:27:38Z
2015-10-29T18:27:38Z
2015
http://hdl.handle.net/2445/67544
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/67430
The zebrafish embryo has emerged as promising
alternative
model for traditional in vivo developmental toxicological
screening due to their advantageous characteristics as their small size
and transparency. In this paper, we reviewed the applicability of the
zebrafish embryo model in some relevant areas to human t
oxicology
as developmental toxicity, cardiovascular toxicity and neurotoxicity
(behavioral assessment). Despite the promising results, further
optimization and testing of more substances as well as a harmonized
methodology is needed to streamline the metho
ds and make the assay
conducive to medium
-
throughput.
19 p.
application/pdf
eng
Research Signpost
Reproducció del capítol del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=249
Recent Advances in Pharmaceutical Sciences V, 2015, Research Signpost. Editors: Diego Muñoz Torrero, M. Pilar Vinardell & Javier Palazón. ISBN: 978-81-308-0561-0. Chapter 5, p. 65-83.
http://hdl.handle.net/2445/67430
(c) Research Signpost, 2015
info:eu-repo/semantics/openAccess
Peix zebra
Toxicologia
Zebra fish
Toxicology
Zebrafish as a model for developmental toxicity assessment
info:eu-repo/semantics/bookPart
oai:recercat.cat:2072/2678742017-10-12T05:34:43Zhdl_2072_179329
RECERCAT (Diposit de la Recerca de Catalunya)
Universitat de Barcelona
authorBoix Sabrià, Núria
authorTeixidó Condomines, Elisabet
authorVila-Cejudo, Marta
authorOrtiz, Pedro
authorIbáñez, Elena
authorGómez Catalán, Jesús
authorLlobet Mallafré, Joan M. (Joan Maria)
authorBarenys Espadaler, Marta
2016-11-10T16:51:22Z
2016-11-10T16:51:22Z
2016
http://hdl.handle.net/2445/103571
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/103042
Triclabendazole (TCBZ) is a veterinary drug used against Fasciola hepatica in cattle. The Cajamarca Valley in Peru is an endemic area of fascioliasis with a high infection rate in animals producing milk for human consumption. The administration of TCBZ during the lactating period can lead to TCBZ derivative residues in milk and cheese entering the human food chain. Milk-derivatives from treated animals have been found positive for TCBZ metabolites. One of these metabolites, triclabendazole sulfoxide
(TCBZSO), is embryolethal during early developmental stages in vitro in mouse
and zebrafish. In this study, we have calculated the estimated daily intake (EDI) of
TCBZSO due to milk and cheese consumption among a rural population in
Cajamarca in order to evaluate the associated risk for human embryonic
development. Although the expected maximum plasma concentration of TCBZSO
after a worst-case scenario simulation would be below the reported lowest
observed adverse effect concentration (LOAEC) for embryolethality in vitro
(10 μM), several limitations on the available information for exposure,
bioavailability and interspecies differences still impede the accomplishment of an
accurate risk assessment.
11 p.
application/pdf
eng
Research Signpost
Reproducció del capítol del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=267
Recent Advances in Pharmaceutical Sciences VI, 2016, Research Signpost. Editors: Diego Muñoz Torrero, Àngela Domínguez García & Ma. Ángeles Manresa Presas. ISBN: 978-81-308-0566-5. Chapter 3, p. 37-47.
http://hdl.handle.net/2445/103042
(c) Research Signpost, 2016
info:eu-repo/semantics/openAccess
Embriologia
Cadenes alimentàries (Ecologia)
Toxicitat dels medicaments
Perú
Embryology
Food chains (Ecology)
Drug toxicity
Peru
Risk assessment for human embryonic development of triclabendazole residues in milk and cheese in the diet of a rural population in Cajamarca (Peru): A preliminary approach
info:eu-repo/semantics/bookPart
oai:recercat.cat:2072/3067742018-03-16T06:33:16Zhdl_2072_179329
RECERCAT (Diposit de la Recerca de Catalunya)
Universitat de Barcelona
authorTorras Claveria, Laura
authorTallini, Luciana
authorViladomat Meya, Francesc
authorBastida Armengol, Jaume
2018-03-15T15:43:36Z
2018-03-15T15:43:36Z
2017
http://hdl.handle.net/2445/120781
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/120717
14 p.
application/pdf
eng
Research Signpost
Reproducció del capítol del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=271
Recent Advances in Pharmaceutical Sciences VII, 2017, Research Signpost. Editors: Diego Muñoz-Torrero, Montserrat Riu & Carles Feliu. ISBN: 978-81-308-0573-3. Chapter 5, p. 69-82.
http://hdl.handle.net/2445/120717
http://hdl.handle.net/2445/102073
(c) Research Signpost, 2017
info:eu-repo/semantics/openAccess
Plantes ornamentals
Amaril·lidàcies
Compostos bioactius
Ornamental plants
Amaryllidaceae
Bioactive compounds
Research in natural products: Amaryllidaceae ornamental plants as sources of bioactive compounds
info:eu-repo/semantics/bookPart
oai:recercat.cat:2072/3067752018-03-16T06:33:16Zhdl_2072_179329
RECERCAT (Diposit de la Recerca de Catalunya)
Universitat de Barcelona
authorDelgado, Lídia
authorLópez-Iglesias, Carmen
authorMercadé Gil, M. Elena
2018-03-15T15:50:55Z
2018-03-15T15:50:55Z
2017
http://hdl.handle.net/2445/120784
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/120717
18 p.
application/pdf
eng
Research Signpost
Reproducció del capítol del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=271
Recent Advances in Pharmaceutical Sciences VII, 2017, Research Signpost. Editors: Diego Muñoz-Torrero, Montserrat Riu & Carles Feliu. ISBN: 978-81-308-0573-3. Chapter 6, p. 83-100.
http://hdl.handle.net/2445/120717
http://hdl.handle.net/2445/102424
(c) Research Signpost, 2017
info:eu-repo/semantics/openAccess
Bacteris
Microscòpia electrònica
Tomografia
Bacteria
Electron microscopy
Tomography
Deciphering the stack, a novel bacterial structure, by (cryo-) transmission electron microscopy and (cryo-) electron tomography
info:eu-repo/semantics/bookPart
oai:recercat.cat:2072/3067102018-03-20T06:35:13Zhdl_2072_179329
RECERCAT (Diposit de la Recerca de Catalunya)
Universitat de Barcelona
authorVallès Xirau, Joan, 1959-
authorD'Ambrosio, Ugo
authorGras, Airy
authorParada i Soler, Montserrat, 1968-
authorRigat i Coll, Montserrat, 1966-
authorSerrasolses, Ginesta
authorGarnatje i Roca, Teresa
2018-03-14T15:42:34Z
2018-03-14T15:42:34Z
2017
http://hdl.handle.net/2445/120724
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/120717
17 p.
application/pdf
eng
Research Signpost
Reproducció del capítol del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=271
Recent Advances in Pharmaceutical Sciences VII, 2017, Research Signpost. Editors: Diego Muñoz-Torrero, Montserrat Riu & Carles Feliu. ISBN: 978-81-308-0573-3. Chapter 1, p. 1-17.
http://hdl.handle.net/2445/120717
http://hdl.handle.net/2445/96459
(c) Research Signpost, 2017
info:eu-repo/semantics/openAccess
Etnobotànica
Plantes medicinals
Aliments funcionals
Ethnobotany
Medicinal plants
Functional foods
Medicinal and food plants in ethnobotany and ethnopharmacology: Folk functional foods in Catalonia (Iberian Peninsula)
info:eu-repo/semantics/bookPart
oai:recercat.cat:2072/3067712018-03-20T06:35:14Zhdl_2072_179329
RECERCAT (Diposit de la Recerca de Catalunya)
Universitat de Barcelona
authorRodríguez Lagunas, María José
authorAzagra Boronat, Ignasi
authorSaldaña-Ruíz, Sandra
authorMassot Cladera, Malen
authorRigo-Adrover, María del Mar
authorSabaté-Jofre, Anna
authorFranch i Masferrer, Àngels
authorCastell, Margarida
authorPérez-Cano, Francisco J.
2018-03-15T13:17:17Z
2018-03-15T13:17:17Z
2017
http://hdl.handle.net/2445/120771
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/120717
16 p.
application/pdf
eng
Research Signpost
Reproducció del capítol del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=271
Recent Advances in Pharmaceutical Sciences VII, 2017, Research Signpost. Editors: Diego Muñoz-Torrero, Montserrat Riu & Carles Feliu. ISBN: 978-81-308-0573-3. Chapter 2, p. 19-34.
http://hdl.handle.net/2445/120717
http://hdl.handle.net/2445/96733
(c) Research Signpost, 2017
info:eu-repo/semantics/openAccess
Probiòtics
Llet materna
Immunologia
Probiotics
Breast milk
Immunology
Immunomodulatory role of probiotics in early life
info:eu-repo/semantics/bookPart
oai:recercat.cat:2072/3067732018-03-20T06:35:15Zhdl_2072_179329
RECERCAT (Diposit de la Recerca de Catalunya)
Universitat de Barcelona
authorCiudad i Gómez, Carlos Julián
authorSolé Ferré, Anna
authorFélix, Alex J.
authorNoé Mata, Verónica
2018-03-15T13:49:45Z
2018-03-15T13:49:45Z
2017
http://hdl.handle.net/2445/120773
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/120717
18 p.
application/pdf
eng
Research Signpost
Reproducció del capítol del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=271
Recent Advances in Pharmaceutical Sciences VII, 2017, Research Signpost. Editors: Diego Muñoz-Torrero, Montserrat Riu & Carles Feliu. ISBN: 978-81-308-0573-3. Chapter 4, p. 51-68.
http://hdl.handle.net/2445/120717
http://hdl.handle.net/2445/101882
(c) Research Signpost, 2017
info:eu-repo/semantics/openAccess
Purines
Nucleòtids
Teràpia genètica
Purines
Nucleotides
Gene therapy
Polypurine Reverse Hoogsteen Hairpins as a tool for gene repair and editing
info:eu-repo/semantics/bookPart
oai:recercat.cat:2072/3067762018-03-20T06:35:16Zhdl_2072_179329
RECERCAT (Diposit de la Recerca de Catalunya)
Universitat de Barcelona
authorGállego, Laia
authorGracenea Zugarramurdi, Mercedes
2018-03-15T16:00:14Z
2018-03-15T16:00:14Z
2017
http://hdl.handle.net/2445/120803
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/120717
14 p.
application/pdf
eng
Research Signpost
Reproducció del capítol del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=271
Recent Advances in Pharmaceutical Sciences VII, 2017, Research Signpost. Editors: Diego Muñoz-Torrero, Montserrat Riu & Carles Feliu. ISBN: 978-81-308-0573-3. Chapter 7, p. 101-114.
http://hdl.handle.net/2445/120717
http://hdl.handle.net/2445/102831
(c) Research Signpost, 2017
info:eu-repo/semantics/openAccess
Parasitologia mèdica
Gastròpodes
Antihelmíntics
Medical parasitology
Gastropods
Anthelmintics
Development of a strategy for the administration of praziquantel to the terrestrial edible snail Cornu aspersum parasitized by Brachylaima sp. metacercariae
info:eu-repo/semantics/bookPart
oai:recercat.cat:2072/3068562018-04-28T05:35:57Zhdl_2072_179329
RECERCAT (Diposit de la Recerca de Catalunya)
Universitat de Barcelona
authorBarniol-Xicota, Marta
authorVázquez Cruz, Santiago
2018-03-19T15:57:47Z
2018-03-19T15:57:47Z
2017
http://hdl.handle.net/2445/120878
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/120717
33 p.
application/pdf
eng
Research Signpost
Reproducció del capítol del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=271
Recent Advances in Pharmaceutical Sciences VII, 2017, Research Signpost. Editors: Diego Muñoz-Torrero, Montserrat Riu & Carles Feliu. ISBN: 978-81-308-0573-3. Chapter 9, p. 133-165.
http://hdl.handle.net/2445/120717
http://hdl.handle.net/2445/98850
(c) Research Signpost, 2017
info:eu-repo/semantics/openAccess
Influenzavirus
Dianes farmacològiques
Química farmacèutica
Influenza viruses
Drug targeting
Pharmaceutical chemistry
Fighting the Influenza A virus. New scaffolds and therapeutic targets
info:eu-repo/semantics/bookPart
oai:recercat.cat:2072/1795312020-02-14T15:06:18Zhdl_2072_179329
RECERCAT (Diposit de la Recerca de Catalunya)
Universitat de Barcelona
authorDuque, María D.
authorTorres, Eva
authorValverde, Elena
authorBarniol-Xicota, Marta
authorGuardiola Bagán, Salvador
authorRey Carrizo, Matías
authorVázquez Cruz, Santiago
2012-01-09T10:46:58Z
2012-01-09T10:46:58Z
2011
257179
http://hdl.handle.net/2445/21371
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/32392
Influenza is a highly contagious, major respiratory tract disease affecting millions of people each year. At present, two classes of antivirals are available: the neuraminidase inhibitors and the M2 proton channel blockers amantadine and rimantadine. However, rapid emergence of M2 blockers resistance makes imperative the development of new anti-influenza drugs. In the last few years several groups have synthesized and evaluated several analogs of amantadine. While several of them are active against wild-type M2 channel only a few are able to inhibit the mutant ion channels that lead to amantadine-resistance.
30 p.
application/pdf
eng
Transworld Research Network
Reproducció del capítol 2 del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=106
Recent Advances in Pharmaceutical Sciences, 2011, Chapter 2, p. 35-64. Editor: Diego Muñoz-Torrero
http://hdl.handle.net/2445/32392
(c) Transworld Research Network, 2011
info:eu-repo/semantics/openAccess
Influenzavirus
Resistència als medicaments
Inhibidors enzimàtics
Influenza viruses
Drug resistance
Enzyme inhibitors
Inhibitors of the M2 channel of influenza A virus
info:eu-repo/semantics/bookPart
oai:recercat.cat:2072/3067092020-02-14T15:06:19Zhdl_2072_179329
RECERCAT (Diposit de la Recerca de Catalunya)
Universitat de Barcelona
authorMuñoz-Torrero López-Ibarra, Diego
authorRiu Aumatell, Montserrat
authorFeliu José, Carlos
2018-03-14T14:31:19Z
2018-03-14T14:31:19Z
2017
978-81-308-0573-3
http://hdl.handle.net/2445/120717
The E-book series Recent Advances in Pharmaceutical Sciences reports research contributions from different areas of the multidisciplinary field of Pharmaceutical Sciences. This seventh volume consists of nine chapters, mainly dealing with the fields of botany, physiology, food
science, biochemistry & molecular biology, plant physiology, microbiology, parasitology, pharmacology, and medicinal chemistry.
171 p.
application/pdf
eng
Research Signpost
Reproducció del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=271
http://www.trnres.com/ebookcontents.php?id=271
http://hdl.handle.net/2445/120724
http://hdl.handle.net/2445/120771
http://hdl.handle.net/2445/120772
http://hdl.handle.net/2445/120773
http://hdl.handle.net/2445/120781
http://hdl.handle.net/2445/120784
http://hdl.handle.net/2445/120803
http://hdl.handle.net/2445/120877
http://hdl.handle.net/2445/120878
(c) Research Signpost, 2017
info:eu-repo/semantics/openAccess
Investigació farmacèutica
Pharmaceutical research
Recent advances in pharmaceutical sciences VII
info:eu-repo/semantics/book
oai:recercat.cat:2072/3544272020-02-14T15:06:20Zhdl_2072_179329
RECERCAT (Diposit de la Recerca de Catalunya)
Universitat de Barcelona
authorFolch López, Jaume
authorEttcheto, Miren
authorBusquets Figueras, Oriol
authorSánchez-López, E. (Elena)
authorCastro Torres, Ruben Dario
authorBeas Zárate, Carlos
authorPallàs i Llibería, Mercè, 1964-
authorOlloquequi González, Jordi
authorJara, Daniela
authorGarcía López, María Luisa
authorAuladell i Costa, M. Carme
authorCamins Espuny, Antoni
2018-03-19T15:42:41Z
2018-03-19T15:42:41Z
2017
http://hdl.handle.net/2445/120877
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/120717
18 p.
application/pdf
eng
Research Signpost
Reproducció del capítol del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=271
Recent Advances in Pharmaceutical Sciences VII, 2017, Research Signpost. Editors: Diego Muñoz-Torrero, Montserrat Riu & Carles Feliu. ISBN: 978-81-308-0573-3. Chapter 8, p. 115-132.
http://hdl.handle.net/2445/120717
http://hdl.handle.net/2445/104227
(c) Research Signpost, 2017
info:eu-repo/semantics/openAccess
Malaltia d'Alzheimer
Medicaments
Alzheimer's disease
Drugs
Strategies against β-amyloid protein as therapeutics in Alzheimer's disease
info:eu-repo/semantics/conferenceObject
oai:recercat.cat:2072/3491952020-02-14T15:06:20Zhdl_2072_179329
RECERCAT (Diposit de la Recerca de Catalunya)
Universitat de Barcelona
authorMuñoz-Torrero López-Ibarra, Diego
authorCajal Visa, Yolanda
authorLlobet Mallafré, Joan M. (Joan Maria)
2019-02-07T09:56:33Z
2019-02-07T09:56:33Z
2018
978-81-308-0579-5
http://hdl.handle.net/2445/128014
This E-book is the eighth volume of a series that compiles contributions
from different areas of the multidisciplinary field of Pharmaceutical
Sciences. The E-book consists of 7 chapters that cover the areas of
organic chemistry, health and environmental management, plant
physiology, food science, toxicology, botany, parasitology, physiology,
biochemistry and molecular biology, microbiology, and pharmacology.
135 p.
application/pdf
eng
Research Signpost
Reproducció del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=287
http://www.trnres.com/ebookcontents.php?id=287
http://hdl.handle.net/2445/128030
http://hdl.handle.net/2445/128069
http://hdl.handle.net/2445/128109
http://hdl.handle.net/2445/128124
http://hdl.handle.net/2445/128128
http://hdl.handle.net/2445/128131
http://hdl.handle.net/2445/128132
(c) Research Signpost, 2018
info:eu-repo/semantics/openAccess
Investigació farmacèutica
Pharmaceutical research
Recent Advances in Pharmaceutical Sciences VIII
info:eu-repo/semantics/book
oai:recercat.cat:2072/3491962020-02-14T15:06:21Zhdl_2072_179329
RECERCAT (Diposit de la Recerca de Catalunya)
Universitat de Barcelona
authorBusquets i Viñas, Ma. Antonia
authorEstelrich i Latràs, Joan
2019-02-07T11:15:08Z
2019-02-07T11:15:08Z
2018
http://hdl.handle.net/2445/128030
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/128014
Magnetic nanoparticles have proven to be promising theranostic agents, namely tools for therapy and diagnosis. Among them, superparamagnetic iron oxide nanoparticles (SPIONs) highlight for their biocompatibility and reduced toxicity. Here, we describe the synthesis and characterization of SPIONs by co-precipitation of ferric and ferrous salts under mild conditions. These particles were able to accumulate in inflamed areas fact that was increased upon the application of an external magnetic field. Resonance magnetic imaging studies have shown their suitability as negative contrast agents for diagnosis. In addition, hybrid nanoparticles were obtained by incorporating the above described SPIONs into liposomes or nanoemulsions. The findings have confirmed the high potential of these systems for biomedical applications.
18 p.
application/pdf
eng
Research Signpost
Reproducció del capítol del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=271
Recent Advances in Pharmaceutical Sciences VIII, 2018, Research Signpost. Editors: Diego Muñoz-Torrero, Yolanda Cajal and Joan Maria Llobet. ISBN: 978-81-308-0579-5. Chapter 1, p. 1-18
http://hdl.handle.net/2445/128014
http://hdl.handle.net/2445/108834
(c) Research Signpost, 2018
info:eu-repo/semantics/openAccess
<a href="http://creativecommons.org/publicdomain/zero/1.0/">http://creativecommons.org/publicdomain/zero/1.0/</a>
Nanopartícules
Magnetisme
Diagnòstic
Terapèutica
Nanoparticles
Magnetism
Diagnosis
Therapeutics
Magnetic nanoparticles: From diagnosis to therapy
info:eu-repo/semantics/bookPart
oai:recercat.cat:2072/3497222020-02-14T15:06:22Zhdl_2072_179329
RECERCAT (Diposit de la Recerca de Catalunya)
Universitat de Barcelona
authorMuñoz-Torrero López-Ibarra, Diego
authorPérez Areales, Francisco Javier
2019-02-11T08:40:00Z
2019-02-11T08:40:00Z
2018
http://hdl.handle.net/2445/128109
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/128014
Alzheimer’s disease (AD) is the main neurodegenerative disorder worldwide. Its pathogenesis involves a network where various mechanisms are interconnected. This complex pathological network makes it extremely challenging to find an efficacious treatment. Herein, we give an overview on the design of the so-called multi-target-directed ligands, i.e. compounds that concurrently hit several key pathogenic factors within the network, as a realistic option to tackle AD, with a particular emphasis on some structural classes of multitarget hybrids recently developed in our group.
16 p.
application/pdf
eng
Research Signpost
Reproducció del capítol del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=287
Recent Advances in Pharmaceutical Sciences VIII, 2018, Research Signpost. Editors: Diego Muñoz-Torrero, Yolanda Cajal and Joan Maria Llobet. ISBN: 978-81-308-0579-5. Chapter 3, p. 43-58
http://hdl.handle.net/2445/128014
http://hdl.handle.net/2445/115549
(c) Research Signpost, 2018
info:eu-repo/semantics/openAccess
<a href="http://creativecommons.org/publicdomain/zero/1.0/">http://creativecommons.org/publicdomain/zero/1.0/</a>
Desenvolupament de medicaments
Malaltia d'Alzheimer
Química farmacèutica
Drug development
Alzheimer's disease
Pharmaceutical chemistry
Development of hybrid compounds to tackle Alzheimer’s disease
info:eu-repo/semantics/bookPart
oai:recercat.cat:2072/3497232020-02-14T15:06:22Zhdl_2072_179329
RECERCAT (Diposit de la Recerca de Catalunya)
Universitat de Barcelona
authorCabezón Rodríguez, Itsaso
authorAugé Marí, Elisabet
authorCamins Espuny, Antoni
authorVilaplana i Hortensi, Jordi
authorPelegrí i Gabaldà, Carme
2019-02-11T10:04:26Z
2019-02-11T10:04:26Z
2018
http://hdl.handle.net/2445/128124
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/128014
Numerous strategies have been proposed to overcome the blood-brain barrier (BBB) and efficiently deliver therapeutic agents to the brain. One of these strategies consists of linking the pharmacologically active substance to a molecular vector that acts as a molecular Trojan Horse and is capable of crossing the BBB using a receptor-mediated transcellular transport system of the brain capillary endothelial cells (BCECs). The transferrin receptor (TfR) is related to a transcytosis process in these cells, and the 8D3 monoclonal antibody (mAb), directed against the mouse TfR, is able to induce a receptor response. Thus, the 8D3 antibody could be a potential molecular Trojan Horse to transport pharmacologically active substances across the BBB. On these bases, a series of experiments were performed where the 8D3 antibody was conjugated to different cargoes, the resulting constructs were administered in vivo to mice, and the distribution and intracellular mechanisms that these constructs undergo at the BBB were
studied. Our results indicated a TfR-mediated and clathrin-dependent internalization
process by which the 8D3-cargo constructs enters the BCEC. The resulting endocytic
vesicles follow at least two different routes. On one hand, most vesicles enter intracellular
processes of vesicular fusion and rearrangement in which the cargo is guided to late
endosomes, multivesicular bodies or lysosomes. On the other hand, a small but not
negligible percentage of the vesicles follow a different route in which they fuse with the
abluminal membrane and open towards the basal lamina, indicating a potential route for
the delivery of therapeutic substances. In this route, however, the 8D3−cargo remain fixed
to the abluminal membrane, indicating that the 8D3 is maintained linked to the TfR, and
the cargo does not go beyond the basal membrane. Altogether, different optimization
approaches need to be developed for efficient drug delivery, but receptor-mediated
transport (RMT) continues to be one of the most promising strategies to overcome the
BBB.
20 p.
application/pdf
eng
Research Signpost
Reproducció del capítol del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=287
Recent Advances in Pharmaceutical Sciences VIII, 2018, Research Signpost. Editors: Diego Muñoz-Torrero, Yolanda Cajal and Joan Maria Llobet. ISBN: 978-81-308-0579-5. Chapter 4, p. 59-78
http://hdl.handle.net/2445/128014
http://hdl.handle.net/2445/115816
(c) Research Signpost, 2018
info:eu-repo/semantics/openAccess
<a href="http://creativecommons.org/publicdomain/zero/1.0/">http://creativecommons.org/publicdomain/zero/1.0/</a>
Fisiologia animal
Barrera hematoencefàlica
Animal physiology
Blood-brain barrier
Study of the transport of substances across the blood-brain barrier with the 8D3 anti-transferrin receptor antibody
info:eu-repo/semantics/bookPart
oai:recercat.cat:2072/3497242020-02-14T15:06:23Zhdl_2072_179329
RECERCAT (Diposit de la Recerca de Catalunya)
Universitat de Barcelona
authorArteaga, Cristina
authorBoix Sabrià, Núria
authorBarenys Espadaler, Marta
authorLlobet Mallafré, Joan M. (Joan Maria)
authorGómez Catalán, Jesús
2019-02-11T10:43:52Z
2019-02-11T10:43:52Z
2018
http://hdl.handle.net/2445/128128
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/128014
The principal aim of this work was to optimize and apply a zebrafish experimental model for the screening of anti-inflammatory substances present in the Mediterranean diet. The zebrafish is an organism widely used in various fields of experimental biology. The inflammation is easily inducible, reproducible and visualized in their early stages of development. Specifically, the migration of neutrophils to the injured caudal fin, one of the first steps of the inflammatory response, is quantitatively measured by image analysis. The anti-inflammatory effect of natural compounds can be evaluated as a decrease of migration. Adverse effects triggered by inflammation are mainly mediated by reactive oxygen species. The anti-oxidant activity of compounds was evaluated in zebrafish embryo measuring their protective effect against tert-butyl hydroperoxide toxicity. Several phenolic compounds have been assayed. Our results showed that the compounds with the greatest decrease on neutrophil migration were chlorogenic acid and cyanidin. The activity of these two polyphenols was quite similar to that observed with anti-inflammatory drugs (indomethacin, piroxicam) and NADPH oxidase inhibitor compounds (dibenzoidolium, apocynin). The anti-inflammatory and the anti-oxidant activity of the assayed polyphenols did not show a clear correlation.
15 p.
application/pdf
eng
Research Signpost
Reproducció del capítol del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=287
Recent Advances in Pharmaceutical Sciences VIII, 2018, Research Signpost. Editors: Diego Muñoz-Torrero, Yolanda Cajal and Joan Maria Llobet. ISBN: 978-81-308-0579-5. Chapter 5, p. 79-94
http://hdl.handle.net/2445/128014
http://hdl.handle.net/2445/116442
(c) Research Signpost, 2018
info:eu-repo/semantics/openAccess
<a href="http://creativecommons.org/publicdomain/zero/1.0/">http://creativecommons.org/publicdomain/zero/1.0/</a>
Peix zebra
Toxicologia
Zebra danio
Toxicology
Evaluation of anti-inflammatory activity of food compounds using zebrafish
info:eu-repo/semantics/bookPart
oai:recercat.cat:2072/3497252020-02-14T15:06:23Zhdl_2072_179329
RECERCAT (Diposit de la Recerca de Catalunya)
Universitat de Barcelona
authorRoca Geronès, Xavier
authorMontoliu Sanllehy, Isabel de
2019-02-11T10:55:27Z
2019-02-11T10:55:27Z
2018
http://hdl.handle.net/2445/128131
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/128014
The presence of ascaridoid nematodes in commonly consumed fish constitutes an important health risk for humans as well as an economic problem for fisheries. Here, information is provided on the taxonomic status of the representative “anisakid-related” species of the families Anisakidae and Raphidascarididae. These parasites have a worldwide marine geographical distribution, mainly related to the presence of the vertebrate hosts involved in their life cycle. Morphological and molecular methods currently used for specific characterization of larval and adult nematode specimens are analysed and discussed. This study is focused on the taxonomy and parasite-host distribution of species of the genera Anisakis and Hysterothylacium from the North-East Atlantic Ocean and Mediterranean Sea regions.
24 p.
application/pdf
eng
Research Signpost
Reproducció del capítol del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=287
Recent Advances in Pharmaceutical Sciences VIII, 2018, Research Signpost. Editors: Diego Muñoz-Torrero, Yolanda Cajal and Joan Maria Llobet. ISBN: 978-81-308-0579-5. Chapter 6, p. 95-118
http://hdl.handle.net/2445/128014
http://hdl.handle.net/2445/117885
(c) Research Signpost, 2018
info:eu-repo/semantics/openAccess
<a href="http://creativecommons.org/publicdomain/zero/1.0/">http://creativecommons.org/publicdomain/zero/1.0/</a>
Nematodes
Peixos
Biogeografia
Parasitologia
Nematodes
Fishes
Biogeography
Parasitology
Biogeography of Anisakis (Anisakidae) and Hysterothylacium (Rhaphidascarididae) nematode species in consumed fish
info:eu-repo/semantics/bookPart
oai:recercat.cat:2072/3497262020-02-14T15:06:24Zhdl_2072_179329
RECERCAT (Diposit de la Recerca de Catalunya)
Universitat de Barcelona
authorCañigueral i Folcarà, Salvador
authorFrommenwiler, Débora
authorReich, Eike
authorVila Casanovas, Roser
2019-02-11T11:24:19Z
2019-02-11T11:24:19Z
2018
http://hdl.handle.net/2445/128132
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/128014
The introduction of high performance thin-layer chromatography (HPTLC) for quality control of herbal products, using standardised methodology and system suitability tests for the qualification of the plates, has improved reproducibility. The use of intensity markers implemented by the Ph. Eur. improved the description and interpretation of the chromatograms. Quantitative information can be retrieved from the electronic images of the chromatograms and used for comprehensive HPTLC fingerprinting: a single HPTLC analysis gives information on identity, purity and content of an herbal drug/preparation/product, simplifying the quality control.
18 p.
application/pdf
eng
Research Signpost
Reproducció del capítol del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=287
Recent Advances in Pharmaceutical Sciences VIII, 2018, Research Signpost. Editors: Diego Muñoz-Torrero, Yolanda Cajal and Joan Maria Llobet. ISBN: 978-81-308-0579-5. Chapter 7, p. 119-136
http://hdl.handle.net/2445/128014
http://hdl.handle.net/2445/110392
(c) Research Signpost, 2018
info:eu-repo/semantics/openAccess
<a href="http://creativecommons.org/publicdomain/zero/1.0/">http://creativecommons.org/publicdomain/zero/1.0/</a>
Cromatografia de capa prima
Control de qualitat
Plantes medicinals
Thin layer chromatography
Quality control
Medicinal plants
High performance thin-layer chromatography (HPTLC) in the quality control of herbal products
info:eu-repo/semantics/bookPart
oai:recercat.cat:2072/2021622020-02-14T15:06:24Zhdl_2072_179329
RECERCAT (Diposit de la Recerca de Catalunya)
Universitat de Barcelona
authorJunyent Herena, Fèlix
authorVerdaguer Cardona, Ester
authorFolch López, Jaume
authorBeas Zárate, Carlos
authorPallàs i Llibería, Mercè, 1964-
authorAuladell i Costa, M. Carme
authorCamins Espuny, Antoni
2012-10-04T10:37:46Z
2012-10-04T10:37:46Z
2012
http://hdl.handle.net/2445/32186
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/32393
The c-Jun N-terminal kinases (JNK) are members of the MAPK family and can be activated by different stimuli such as cellular stress, heat shock and ultra-violet irradiation. JNKs have different physiological functions and they have been linked to apoptosis in different cell types. Therefore, the JNK signalling pathway is an important target to prevent cell death. In the present chapter, the role of JNKs in neurodegenerative diseases will be discussed, as well as the pharmacological compounds that inhibit this signalling pathway as therapeutic intervention to prevent neuronal death.
14 p.
application/pdf
eng
Transworld Research Network
Reproducció del capítol 2 del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=131
Recent Advances in Pharmaceutical Sciences II, 2012, Editor: Diego Muñoz-Torrero, Diego Haro and Joan Vallès, Chapter 2, p. 15-28.
http://hdl.handle.net/2445/32393
(c) Transworld Research Network, 2012
info:eu-repo/semantics/openAccess
Farmacologia
Malalties neurodegeneratives
Pharmacology
Neurodegenerative diseases
Role of JNK in neurodegenerative diseases
info:eu-repo/semantics/bookPart
oai:recercat.cat:2072/3712872020-02-14T15:06:25Zhdl_2072_179329
RECERCAT (Diposit de la Recerca de Catalunya)
Universitat de Barcelona
authorMuñoz-Torrero López-Ibarra, Diego
authorCortés Lucas, Amparo
authorMariño Hernández, Eduardo L.
2013-10-15T11:39:22Z
2013-10-15T11:39:22Z
2013
978-81-7895-605-3
http://hdl.handle.net/2445/46988
209 p.
application/pdf
eng
Transworld Research Network
Reproducció del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=164
https://cercabib.ub.edu/iii/encore/record/C__Rb2094706
http://hdl.handle.net/2445/46989
http://hdl.handle.net/2445/46991
http://hdl.handle.net/2445/46992
http://hdl.handle.net/2445/46994
http://hdl.handle.net/2445/46996
http://hdl.handle.net/2445/46997
http://hdl.handle.net/2445/46999
http://hdl.handle.net/2445/47000
http://hdl.handle.net/2445/47001
http://hdl.handle.net/2445/47002
http://hdl.handle.net/2445/47003
http://hdl.handle.net/2445/47004
(c) Transworld Research Network, 2013
info:eu-repo/semantics/openAccess
Investigació farmacèutica
Pharmaceutical research
Recent advances in pharmaceutical sciences III
info:eu-repo/semantics/book
oai:recercat.cat:2072/2198182020-02-14T15:06:25Zhdl_2072_179329
RECERCAT (Diposit de la Recerca de Catalunya)
Universitat de Barcelona
authorPenon Esteva, Oriol
authorRodrigues, Ana Mafalda Nunes
authorPérez García, M. Lluïsa (Maria Lluïsa)
2013-10-15T11:51:03Z
2013-10-15T11:51:03Z
2013
http://hdl.handle.net/2445/46989
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/46988
Mimicking Nature, supramolecular chemistry represents the chemistry beyond the molecule, in view that intermolecular
interactions constitute the driving force for the preparation of molecular and supramolecular assemblies, using the chemical
information contained in molecular building blocks. Upon molecular recognition between discrete units, chemical processes
such as self-assembly and self-organisation start operating, and are the leading processes to build up supramolecular aggregates and materials. When those materials have dimensions on the
nanometric scale, a recently emerging scientific discipline is defined,
Nanoscience. Nanomaterials are promising tools for many applications, and their use in biomedical and clinical applications
defines the so-called Nanomedicine. In this review we present a few selected examples of nanomaterials designed for therapeutical purposes, emphasizing the importance of the preparation methodology in terms of their therapeutical use.
22 p.
application/pdf
eng
Transworld Research Network
Capítol del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=164
Recent Advances in Pharmaceutical Sciences III, 2013, Transworld Research Network : Editors: Diego Muñoz Torrero, Amparo Cortés & Eduardo L. Mariño. ISBN: 978-81-7895-605-3. Chapter 1, p. 1-22.
http://hdl.handle.net/2445/46988
(c) Transworld Research Network, 2013
info:eu-repo/semantics/openAccess
Investigació farmacèutica
Química supramolecular
Nanomedicina
Pharmaceutical research
Supramolecular chemistry
Nanomedicine
Supramolecular chemistry for nanomedicine
info:eu-repo/semantics/bookPart
oai:recercat.cat:2072/2198192020-02-14T15:06:26Zhdl_2072_179329
RECERCAT (Diposit de la Recerca de Catalunya)
Universitat de Barcelona
authorVila Casanovas, Roser
authorFreixa de Reynoso, Blanca
authorCañigueral i Folcarà, Salvador
2013-10-15T11:58:04Z
2013-10-15T11:58:04Z
2013
http://hdl.handle.net/2445/46991
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/46988
Due to the increase of the incidence of fungal infections in humans and the limitations of the available antimycotic drugs, among which the emergence of resistant strains, there is a need for the discovery of new antifungal agents. Plants, especially those used in Traditional Medicine, linked to an unmatched chemical diversity, either as pure compounds or as plant extracts, provide unlimited opportunities for the development of new antifungals. In
recent years, compounds from different phytochemical groups have been described as having antifungal activity, including polyphenols, saponins, or peptides, among others, as well as
essential oils and their constituents. After screening of ethnopharmacologically selected plants, mainly from Latin-America, followed by bio-guided isolation, our group has
described the antifungal activity of different types of plant constituents, such as sesquiterpenes, triterpenes, flavonoids, lignans, fatty acids and essential oils.
21 p.
application/pdf
eng
Transworld Research Network
Reproducció del capítol del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=164
Recent Advances in Pharmaceutical Sciences III, 2013, Transworld Research Network : Editors: Diego Muñoz Torrero, Amparo Cortés & Eduardo L. Mariño. ISBN: 978-81-7895-605-3. Chapter 2, p. 23-43.
http://hdl.handle.net/2445/46988
(c) Transworld Research Network, 2013
info:eu-repo/semantics/openAccess
Investigació farmacèutica
Medicaments antifúngics
Plantes medicinals
Pharmaceutical research
Antifungal agents
Medicinal plants
Antifungal compounds from plants
info:eu-repo/semantics/bookPart
oai:recercat.cat:2072/3712882020-02-14T15:06:27Zhdl_2072_179329
RECERCAT (Diposit de la Recerca de Catalunya)
Universitat de Barcelona
authorMuñoz-Torrero López-Ibarra, Diego
authorVázquez Carrera, Manuel
authorEstelrich i Latràs, Joan
2015-03-05T13:06:03Z
2015-03-05T13:06:03Z
2014
978-81-308-0554-2
http://hdl.handle.net/2445/63704
Reproducció del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=234
Like in the three previous editions, this E-book compiles a series of
contributions in the multidisciplinary research arena of Pharmaceutical
Sciences. The E-book has been organized in 12 chapters, whose main topics
belong to the fields of pharmacology, physical chemistry, plant physiology,
microbiology, physiology, preventive medicine and public health, food
science, botany, clinical pharmacy and pharmacotherapy, organic
chemistry, biochemistry and molecular biology, and parasitology...
205 p.
application/pdf
eng
Research Signpost
https://cercabib.ub.edu/iii/encore/record/C__Rb2144110
http://hdl.handle.net/2445/63891
http://hdl.handle.net/2445/63970
http://hdl.handle.net/2445/63971
http://hdl.handle.net/2445/63972
http://hdl.handle.net/2445/63973
http://hdl.handle.net/2445/64323
http://hdl.handle.net/2445/64324
http://hdl.handle.net/2445/64325
http://hdl.handle.net/2445/64366
http://hdl.handle.net/2445/64367
http://hdl.handle.net/2445/64368
http://hdl.handle.net/2445/64369
(c) Transworld Research Network, 2014
info:eu-repo/semantics/openAccess
Investigació farmacèutica
Pharmaceutical research
Recent advances in pharmaceutical sciences IV
info:eu-repo/semantics/book
oai:recercat.cat:2072/3712892020-02-14T15:06:27Zhdl_2072_179329
RECERCAT (Diposit de la Recerca de Catalunya)
Universitat de Barcelona
authorMuñoz-Torrero López-Ibarra, Diego
authorVinardell Martínez-Hidalgo, Ma. Pilar
authorPalazón Barandela, Javier
2015-10-22T16:28:30Z
2015-10-22T16:28:30Z
2015
978-81-308-0561-0
http://hdl.handle.net/2445/67430
Reproducció del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=249
This E-book is the fifth volume of a series that compiles contributions
from different areas of the multidisciplinary field of Pharmaceutical
Sciences. The E-book consists of 11 chapters that cover the areas of
organic chemistry, health and environmental management, plant
physiology, food science, toxicology, botany, parasitology, physiology,
biochemistry and molecular biology, microbiology, and pharmacology.
190 p.
application/pdf
eng
Research Signpost
https://cercabib.ub.edu/iii/encore/record/C__Rb2161419
http://hdl.handle.net/2445/67431
http://hdl.handle.net/2445/67541
http://hdl.handle.net/2445/67542
http://hdl.handle.net/2445/67543
http://hdl.handle.net/2445/67544
http://hdl.handle.net/2445/67557
http://hdl.handle.net/2445/67558
http://hdl.handle.net/2445/67560
http://hdl.handle.net/2445/67561
http://hdl.handle.net/2445/67563
http://hdl.handle.net/2445/67564
(c) Research Signpost, 2015
info:eu-repo/semantics/openAccess
Investigació farmacèutica
Pharmaceutical research
Recent advances in pharmaceutical sciences V
info:eu-repo/semantics/book
oai:recercat.cat:2072/3712902020-02-14T15:06:27Zhdl_2072_179329
RECERCAT (Diposit de la Recerca de Catalunya)
Universitat de Barcelona
authorMuñoz-Torrero López-Ibarra, Diego
authorDomínguez García, Àngela
authorManresa Presas, Ma. Ángeles (María Ángeles)
2016-10-28T14:00:02Z
2016-10-28T14:00:02Z
2016
978-81-308-0566-5
http://hdl.handle.net/2445/103042
This E-book is the sixth volume of a series that compiles contributions from different areas of the multidisciplinary field of Pharmaceutical Sciences, particularly phisical chemistry, food science, toxicology, botany, biochemistry and molecular biology, preventive medicine and public health, pharmacology, physiology, microbiology, and parasitology.
214 p.
application/pdf
eng
Research Signpost
Reproducció del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=267
https://cercabib.ub.edu/iii/encore/record/C__Rb2198581
http://www.trnres.com/ebookcontents.php?id=267
http://hdl.handle.net/2445/103043
http://hdl.handle.net/2445/103448
http://hdl.handle.net/2445/103571
http://hdl.handle.net/2445/103608
http://hdl.handle.net/2445/103662
http://hdl.handle.net/2445/104142
http://hdl.handle.net/2445/104143
http://hdl.handle.net/2445/104144
http://hdl.handle.net/2445/104173
http://hdl.handle.net/2445/104174
http://hdl.handle.net/2445/104176
(c) Research Signpost, 2016
info:eu-repo/semantics/openAccess
Investigació farmacéutica
Pharmaceutical research
Recent Advances in Pharmaceutical Sciences VI
info:eu-repo/semantics/book
oai:recercat.cat:2072/3712912020-02-14T15:06:27Zhdl_2072_179329
RECERCAT (Diposit de la Recerca de Catalunya)
Universitat de Barcelona
authorPubill Sánchez, David
authorCiudad Roberts, Andrés
authorDuart Castells, Leticia
authorCiudad i Gómez, Carlos Julián
authorCamarasa García, Jordi
authorEscubedo Rafa, Elena
2016-11-24T16:22:51Z
2016-11-24T16:22:51Z
2016
http://hdl.handle.net/2445/104143
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/103042
In the last decade, a new family of synthetic psychostimulant drugs, under the name of cathinones, broke into the market. These drugs are mainly consumed by adolescents and young adults with recreational purposes, in most cases combined with alcoholic drinks. Although a number of works about new cathinones have been recently published, none explored the consequences of such combination. Because adolescence is a crucial period in brain development, we sought to study the effects of the combination of mephedrone plus ethanol in adolescent mice, focusing on psychostimulant and conditioning effects, as well as on neurotoxicity markers. Ethanol increased both locomotor activity and conditioned place preference (CPP) induced by mephedrone. RNA microarray assays after CPP test yielded significant alterations in neuronal plasticity-related genes and a key role of BDNF and dopamine D3 receptors in CPP acquisition was found. Ethanol potentiated the oxidative stress as well as the decreases in dopaminergic and serotonergic markers in frontal cortex and hippocampus respectively, after a binge treatment with mephedrone. Moreover, the drug combination impaired spatial learning and memory, as well as neurogenesis to a higher extent than mephedrone alone.
19 p.
application/pdf
eng
Research Signpost
Reproducció del capítol del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=267
Recent Advances in Pharmaceutical Sciences VI, 2016, Research Signpost. Editors: Diego Muñoz Torrero, Àngela Domínguez García & Ma. Ángeles Manresa Presas. ISBN: 978-81-308-0566-5. Chapter 7, p. 111-129
http://hdl.handle.net/2445/103042
(c) Research Signpost, 2016
info:eu-repo/semantics/openAccess
Drogues de disseny
Consum d'alcohol
Adolescents
Designer drugs
Drinking of alcoholic beverages
Teenagers
Neuropsychopharmacologic and neurotoxicologic effects of the combination of ethanol with mephedrone in adolescent mice
info:eu-repo/semantics/bookPart